I guess my research was incomplete since I overlooked
this, which, I believe, answers my question.
A few paragraphs down, in the discussion of manually partitioning a 4K disk using older Linux tools, it states:
Make sure that all partitions start on a multiple of 8 sectors (8x 512B = 4KB) and that partition sizes are multiples of 8 sectors. Make sure that there is space left at the start of partitions as required. For example on a boot drive, do not start at sector 0 as there needs to be space for the boot code. Sector 64 is a good start point or even 2048 which would be a 1MB boundary. Also extended partitions will need a gap between their start point and the first logical partition contained within them.
Since Western Digital was the first company to introduce 4K drives, I assume they know what they're talking about.
I'm posting this before my OP was moderated, so thanks to anyone who responds to the OP before they read this.